MXD4 Antibody - N-terminal region : Biotin
Katalog-Nummer ARP32777_P050-Biotin
Size : 100ul
Marke : Aviva Systems Biology
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MXD4 Antibody - N-terminal region : Biotin (ARP32777_P050-Biotin)
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| Datasheets/Manuals | Printable datasheet for anti-MXD4 (ARP32777_P050-Biotin) antibody |
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| Predicted Species Reactivity | Human, Mouse, Cow, Dog, Guinea Pig, Rabbit, Sheep |
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| Product Format | Liquid. Purified antibody supplied in 1x PBS buffer. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | Biotin |
| Application | WB, IHC |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the N terminal region of human MXD4 |
| Purification | Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Sheep: 93% |
| Peptide Sequence | Synthetic peptide located within the following region: SLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNN |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-MXD4 (ARP32777_P050-Biotin) antibody is Catalog # AAP32777 (Previous Catalog # AAPP03792) |
| Reference | Jiang,D.J., et al., (2004) J. Biochem. Mol. Biol. 37 (4), 402-407 |
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| Gene Symbol | MXD4 |
| Gene Full Name | MAX dimerization protein 4 |
| Alias Symbols | MAD4, MST149, MSTP149, bHLHc12 |
| NCBI Gene Id | 10608 |
| Protein Name | Max dimerization protein 4 |
| Description of Target | MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. |
| Uniprot ID | Q14582 |
| Protein Accession # | NP_006445 |
| Nucleotide Accession # | NM_006454 |
| Protein Size (# AA) | 209 |
| Molecular Weight | 24kDa |
| Protein Interactions | TCP10L; UBC; SHBG; SIN3A; MLX; MAX; SMC3; |
