MSH6 Mouse Monoclonal Antibody [Clone ID: OTI5D1]
CAT#: TA807929
MSH6 mouse monoclonal antibody,clone OTI5D1
Size: 30 ul
Formulation: Carrier-Free
Conjugation: Biotin HRP
Product Images
Specifications
| Product Data | |
| Clone Name | OTI5D1 |
| Applications | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivities | Human, Mouse, Rat |
| Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1-280 of human MSH6(NP_000170) produced in E.coli. |
| Formulation | PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
| Concentration | 1 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | mutS homolog 6 |
| Database Link | |
| Background | This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described. [provided by RefSeq, Jul 2013] |
| Synonyms | GTBP; GTMBP; HNPCC5; HSAP; MMRCS3; p160 |
| Reference Data | |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | Colorectal cancer, Mismatch repair, Pathways in cancer |
Documents
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Resources
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Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| CF807929 | Carrier-free (BSA/glycerol-free) MSH6 mouse monoclonal antibody,clone OTI5D1 | 600,00 EUR | |
| TA807929AM | MSH6 mouse monoclonal antibody,clone OTI5D1, Biotinylated | 509,00 EUR | |
| TA807929BM | MSH6 mouse monoclonal antibody,clone OTI5D1, HRP conjugated | 509,00 EUR | |
| TA807929S | MSH6 mouse monoclonal antibody,clone OTI5D1 | 200,00 EUR |