Mouse HADHb (Hydroxyacyl Coenzyme A Dehydrogenase Beta) Sandwich ELISA Kit

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	Hadhb
Gene ID:	231086
Uniprot ID:	ECHB_MOUSE
Sample Type:	tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications	Acetylation of Lys-202 is observed in liver mitochondria from fasted mice but not from fed mice.
Function	Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and is performed through four consecutive reactions breaking down fatty acids into acetyl-CoA. Among the enzymes involved in this pathway, the trifunctional enzyme exhibits specificity for long-chain fatty acids. Mitochondrial trifunctional enzyme is a heterotetrameric complex composed of two proteins, the trifunctional enzyme subunit alpha/HADHA carries the 2,3-enoyl-CoA hydratase and the 3-hydroxyacyl-CoA dehydrogenase activities, while the trifunctional enzyme subunit beta/HADHB described here bears the 3-ketoacyl-CoA thiolase activity.
Protein Name	Trifunctional Enzyme Subunit Beta - Mitochondrial Tp-Beta Includes - 3-Ketoacyl-Coa Thiolase Acetyl-Coa Acyltransferase Beta-Ketothiolase
Database Links	Reactome: R-MMU-1482798 Reactome: -MMU-77285 Reactome: -MMU-77305 Reactome: -MMU-77310 Reactome: -MMU-77346 Reactome: -MMU-77348 Reactome: -MMU-77350
Cellular Localisation	Mitochondrion Mitochondrion Inner Membrane Mitochondrion Outer Membrane Endoplasmic Reticulum Protein Stability And Association With Membranes Require Hadha
Alternative ELISA Names	Trifunctional Enzyme Subunit Beta - Mitochondrial ELISA kit Tp-Beta Includes - 3-Ketoacyl-Coa Thiolase ELISA kit Acetyl-Coa Acyltransferase ELISA kit Beta-Ketothiolase ELISA kit Hadhb ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance