Mouse Gck activation kit by CRISPRa

Katalog-Nummer GA211775

Size : 1kit

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Mouse Gck activation kit by CRISPRa

Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol Gck
Locus ID 103988
Components

GA211775G1, Gck gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA211775G2, Gck gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA211775G3, Gck gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001287386, NM_010292
UniProt ID P52792
Synonyms Gk; GLK; Gls006; HK4; HKIV; Hlb62; HXKP; MODY2
Summary Catalyzes the initial step in utilization of glucose by the beta-cell and liver at physiological glucose concentration. Pancreatic glucokinase plays an important role in modulating insulin secretion. Hepatic glucokinase helps to facilitate the uptake and conversion of glucose by acting as an insulin-sensitive determinant of hepatic glucose usage.[UniProtKB/Swiss-Prot Function]
SKU Description Size
KN506364 Gck - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. 1 kit

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.