Specifications

Product Data
Applications	IHC, WB
Recommended Dilution	WB: 500-2000 WB positive control: Human abdominal interstitial sarcoma tissue, A549, 293T and HepG2 cell lysates IHC: 50-300 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivities	Human
Host	Rabbit
Isotype	IgG
Clonality	Polyclonal
Immunogen	Synthetic peptide peptide corresponding to a region derived from 465-478 amino acids of human solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Predicted Protein Size	52 kDa
Gene Name	solute carrier family 16 member 7
Database Link	NP_004722 Entrez Gene 9194 Human UniProt ID O60669
Background	This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites; such as lactate; pyruvate; and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants.
Synonyms	MCT2
Reference Data
Protein Families	Transmembrane