MBD2 Antibody
Katalog-Nummer OAEB02464
Size : 100ug
Marke : Aviva Systems Biology
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Telefonnummer : +1 850 650 7790
MBD2 Antibody (OAEB02464)
| Datasheets/Manuals | Printable datasheet for MBD2 Antibody (OAEB02464) |
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| Predicted Species Reactivity | Dog|Human|Mouse|Rat |
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| Product Format | Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. |
| Clonality | Polyclonal |
| Host | Goat |
| Application | ELISA|IHC|WB |
| Reconstitution and Storage | -20°C |
| Immunogen | MBD2 (isoform 1) |
| Purification | Ammonium Sulfate Precipitated; Affinity Purified |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 80% |
| Peptide Sequence | C-RNDPLNQNKGKPDLN |
| Concentration | 0.5 mg/ml |
| Purity | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Application Info | Peptide ELISA: antibody detection limit dilution 1:64000. Western Blot: Approx 48-50kDa band observed in lysates of cell line Jurkat (calculated MW of 43.3kDa according to NP_003918.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Tan et al, Mol Cell Biol. 2006 Oct;26(19):7224-35.; PMID: 16980624). Recommended concentration: 0.3-1ug/ml. Immunohistochemistry: In paraffin embedded Human Colon shows nuclear stianing of enterocytes. Recommended concentration, 2-4ug/ml. |
| Reference | * Auriol E, Billard LM, Magdinier F, Dante R.; Specific binding of the methyl binding domain protein 2 at the BRCA1-NBR2 locus.; Nucleic Acids Res. 2005 Jul 28;33(13):4243-54. Print 2005.; Pubmed 16052033 |
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| Gene Symbol | Mbd2|MBD2 |
| Gene Full Name | methyl-CpG binding domain protein 2 |
| Alias Symbols | demethylase, DMTase, MBD2a, methyl-CpG-binding domain protein 2, methyl-CpG-binding protein MBD2, NY-CO-41, testis-specific methyl-CpG binding protein 2. |
| NCBI Gene Id | 17191|8932 |
| Protein Name | methyl-CpG-binding domain protein 2 isoform 1 [Homo sapiens] |
| Uniprot ID | Q9UBB5 |
| Protein Accession # | https://www.ncbi.nlm.nih.gov/protein/NP_003918.1 |
| Molecular Weight | 43.3; 31.7 |
