L-Glutathione reduced [70-18-8]

Katalog-Nummer HY-D0187-5g

Size : 5g

Marke : MedChemExpress

Contact local distributor :


Telefonnummer : +1 850 650 7790

L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Kundenspezifische Peptidsynthese

L-Glutathione reduced Chemische Struktur

L-Glutathione reduced Chemische Struktur

CAS. Nr. : 70-18-8

This product is a controlled substance and not for sale in your territory.

Based on 25 publication(s) in Google Scholar

Other Forms of L-Glutathione reduced:

  • L-Glutathione reduced-13C2,15N Angebot einholen
Beschreibung

L-Glutathione reduced (GSH; γ-L-Glutamyl-L-cysteinyl-glycine) is an endogenous antioxidant and is capable of scavenging oxygen-derived free radicals.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

L-Glutathione reduced is a non-protein thiol widely exists in living cells. L-Glutathione reduced plays important biological functions in the organism, including protein and DNA synthesis, enzyme activity, metabolism and cell protection. L-Glutathione reduced is capable of scavenging oxygen-derived free radicals and is established to be a marker of oxidative stress[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

307.32

Formel

C10H17N3O6S

CAS. Nr.

70-18-8

Appearance

Solid

Color

White to off-white

Structure Classification
  • Ketones, Aldehydes, Acids
Initial Source
  • Endogenous metabolite
  • Human Gut Microbiota Metabolites
  • Microorganisms
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

4°C, protect from light, stored under nitrogen

*The compound is unstable in solutions, freshly prepared is recommended.

Lösungsmittel & Löslichkeit
In Vitro: 

H2O : 62.5 mg/mL (203.37 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2539 mL 16.2697 mL 32.5394 mL
5 mM 0.6508 mL 3.2539 mL 6.5079 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (325.39 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Reinheit & Dokumentation

Purity: 99.87%

Verweise
  • [1]. Pereira-Rodrigues N, et al. Electrocatalytic activity of cobalt phthalocyanine CoPc adsorbed on a graphite electrode for the oxidation of reduced L-glutathione (GSH) and the reduction of its disulfide (GSSG) at physiological pH. Bioelectrochemistry. 2007 Jan;70(1):147-54.  [Content Brief]

  • [1]. Pereira-Rodrigues N, et al. Electrocatalytic activity of cobalt phthalocyanine CoPc adsorbed on a graphite electrode for the oxidation of reduced L-glutathione (GSH) and the reduction of its disulfide (GSSG) at physiological pH. Bioelectrochemistry. 2007 Jan;70(1):147-54.

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.2539 mL 16.2697 mL 32.5394 mL 81.3484 mL
5 mM 0.6508 mL 3.2539 mL 6.5079 mL 16.2697 mL
10 mM 0.3254 mL 1.6270 mL 3.2539 mL 8.1348 mL
15 mM 0.2169 mL 1.0846 mL 2.1693 mL 5.4232 mL
20 mM 0.1627 mL 0.8135 mL 1.6270 mL 4.0674 mL
25 mM 0.1302 mL 0.6508 mL 1.3016 mL 3.2539 mL
30 mM 0.1085 mL 0.5423 mL 1.0846 mL 2.7116 mL
40 mM 0.0813 mL 0.4067 mL 0.8135 mL 2.0337 mL
50 mM 0.0651 mL 0.3254 mL 0.6508 mL 1.6270 mL
60 mM 0.0542 mL 0.2712 mL 0.5423 mL 1.3558 mL
80 mM 0.0407 mL 0.2034 mL 0.4067 mL 1.0169 mL
100 mM 0.0325 mL 0.1627 mL 0.3254 mL 0.8135 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

L-Glutathione reduced Related Classifications

Help & FAQs

Keywords:

L-Glutathione reduced70-18-8GSH γ-L-Glutamyl-L-cysteinyl-glycineEndogenous MetaboliteReactive Oxygen SpeciesFerroptosisInhibitorinhibitorinhibit

Sie könnten auch an folgenden Produkten interessiert sein:



Katalog-Nummer
Beschreibung
Cond.
Preis zzgl. MwSt.
TRC-S080853-10G
 10g 
ELH-Thyroglobulin-1
 1PlateKit