IRS2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommended Dilution	IHC: 50-200 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm
Reactivities	Human, Mouse
Host	Rabbit
Isotype	IgG
Clonality	Polyclonal
Immunogen	Synthetic peptide of human IRS2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage	Store at -20°C.
Stability	1 year
Gene Name	insulin receptor substrate 2
Database Link	Entrez Gene 8660 Human UniProt ID Q9Y4H2
Background	This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Synonyms	IRS-2
Reference Data