Human Phospholipase c eta 1 (PLCH1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLCH1
Locus ID	23007
Kit Components	GA107964G1, Phospholipase c eta 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA107964G2, Phospholipase c eta 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA107964G3, Phospholipase c eta 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001130960, NM_001130961, NM_014996, NM_001349250, NM_001349251, NM_001349252
UniProt ID	Q4KWH8
Synonyms	PLCL3
Summary	PLCH1 is a member of the PLC-eta family of the phosphoinositide-specific phospholipase C (PLC) superfamily of enzymes that cleave phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to generate second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) (Hwang et al., 2005 [PubMed 15702972]).[supplied by OMIM, Jun 2009]