Human MTTP activation kit by CRISPRa

CAT#: GA103028

MTTP CRISPRa kit - CRISPR gene activation of human microsomal triglyceride transfer protein



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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol MTTP
Locus ID 4547
Kit Components

GA103028G1, MTTP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103028G2, MTTP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103028G3, MTTP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_000253, NM_001300785
UniProt ID P55157
Synonyms ABL; MTP
Summary MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia. [provided by RefSeq, Jul 2008]

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