General Info
Applications: | ELISA |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Sensitivity: | 0.058ng/mL |
Detection Limit: | 0.156-10ng/mL |
Short Description: | This COMT Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human cell culture supernatant, serum and plasma (EDTA, citrate, heparin). |
Storage Instruction: | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
Assay Time: | 4.5 hrs |
Information
Gene Symbol: | COMT |
Gene ID: | 1312 |
Uniprot ID: | COMT_HUMAN |
Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
Description
Tissue Specificity | Brain, liver, placenta, lymphocytes and erythrocytes. |
Post Translational Modifications | The N-terminus is blocked. |
Function | Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol. |
Protein Name | Catechol O-Methyltransferase |
Database Links | Reactome: R-HSA-156581Reactome: R-HSA-379397Reactome: R-HSA-379398Reactome: R-HSA-9679191 |
Cellular Localisation | Isoform Soluble: CytoplasmIsoform Membrane-Bound: Cell MembraneSingle-Pass Type Ii Membrane ProteinExtracellular Side |
Alternative ELISA Names | Catechol O-Methyltransferase ELISA kitCOMT ELISA kit |
output |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance