Human CD55 Antibody : PE
Katalog-Nummer OASB02631
Size : 25tests
Marke : Aviva Systems Biology
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Telefonnummer : +1 850 650 7790
Human CD55 Antibody : PE (OASB02631)
| Datasheets/Manuals | Printable datasheet for Human CD55 Antibody : PE (OASB02631) |
|---|
| Tested Species Reactivity | Human |
|---|---|
| Predicted Species Reactivity | Human |
| Product Format | Liquid. Phosphate buffered saline containing 0.1% sodium azide and a stabilizer |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugation | R-PE |
| Application | FC |
| Additional Information | Description: CD55, also known as decay accelerating factor (DAF), is an 80 kDa GPI-anchored single chain glycoprotein that is expressed on all cells in contact with serum including all hematopoietic cells and the vascular endothelium. A soluble form of CD55 is present in plasma and body fluids. CD55 is a member of the regulator of complement activity (RCA) family of proteins and is thought to play a role in the protection of cells from damage by autologous complement by preventing the amplification steps of the complement cascade. CD55 expression increases upon T cell activation and antibodies to CD55 are mitogenic in the presence of phorbol esters. |
| Reconstitution and Storage | Store at 2-8C |
| Immunogen | PHA activated peripheral blood mononuclear cells |
| Concentration | Lot specific |
| Specificity | CD55 |
| Gene Symbol | CD55 |
|---|---|
| Gene Full Name | CD55 molecule (Cromer blood group) |
| Alias Symbols | CR, TC, DAF, CROM, CHAPLE |
| NCBI Gene Id | 1604 |
| Protein Name | complement decay-accelerating factor |
| Description of Target | This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins. |
| Uniprot ID | P08174 |
| Protein Accession # | NP_000565.1 |
| Nucleotide Accession # | NM_000574.4 |
