Biotrend > HLA-DRA Antibody
HLA-DRA Antibody
Katalog-Nummer OAEE01049
Size : 100tests(T100)
Marke : Aviva Systems Biology
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Datasheets/Manuals | Printable datasheet for HLA-DRA Antibody |
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Predicted Species Reactivity | Human|Porcine |
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Product Format | Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
Clonality | Monoclonal |
Clone | HL-38 |
Isotype | IgG2a |
Host | Mouse |
Conjugation | R-PE |
Application | FC |
Reconstitution and Storage | 2°C to 8°C |
Immunogen | Raji Burkitt's lymphoma cell line |
Purification | Purified by size-exclusion chromatography |
Concentration | 20 ul / test |
Specificity | The antibody HL-38 recognizes common epitope on beta-chain of human HLA-DR and HLA-DP. DR and DP are the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages). |
Formulation | PE |
Storage Buffer | The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent. |
Reference | Horejsi V, Nemec M, Angelisova P, Kristofova H, Gorga JC, Hilgert I: Characterization of seven new monoclonal antibodies against human DR, DR + DP and DQ1 + DQ3 antigens. Tissue Antigens. 1986 Nov;28(5):288-97. |
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Gene Symbol | HLA-DRA |
Gene Full Name | HLA class II histocompatibility antigen, DR alpha chain; HLA class II histocompatibility antigen, DP alpha 1 chain |
Alias Symbols | HLA-DRA1 |
NCBI Gene Id | 3122; 3113 |
Protein Name | HLA class II histocompatibility antigen, DR alpha chain |
Uniprot ID | P01903; P20036; |
Protein Accession # | NP_061984.2; NP_001229453.1; NP_001229454.1; NP_291032.2; |
Nucleotide Accession # | NM_019111.4; NM_001242524.1; NM_001242525.1 |
Protein interactions
Name | # of Products |
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ANXA11 | 25 |
ATP1B1 | 30 |
CD63 | 61 |
CD74 | 47 |
CD82 | 185 |
HLA-DMA | 13 |
HLA-DMB | 20 |
HLA-DRB1 | 80 | <
HSP90AA1 | 525 |
HSP90AB1 | 130 |
HSPA8 | 331 |
MBP | 53 |
MS4A1 | 18 |
PKM2 | 47 |
PRPF40B | 7 |
UBC | 7030 |
YWHAE | 312 |
Biological pathways
Name | # of Products |
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Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | 13 |
Interferon-gamma-mediated signaling pathway | 264 |
T cell costimulation | 425 |
T cell receptor signaling pathway | 453 |
Biological process
Name | # of Products |
---|---|
Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | 11 |
Cytokine-mediated signaling pathway | 229 |
Immune response | 404 |
Interferon-gamma-mediated signaling pathway | 61 |
T cell costimulation | 87 |
T cell receptor signaling pathway | 90 |
Cellular components
Name | # of Products |
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Endoplasmic reticulum | 837 |
Endoplasmic reticulum membrane | 498 |
Endosome | 258 |
Golgi apparatus | 794 |
Integral to membrane | 2793 |
Integral to plasma membrane | 817 |
Late endosome membrane | 46 |
Lysosomal membrane | 90 |
Lysosome | 161 |
Membrane | 2769 |
MHC class II protein complex | 12 |
Plasma membrane | 2678 |
Protein function
Name | # of Products |
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MHC class II receptor activity | 18 |
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