Histone Acetyltransferase Inhibitor IV, CPTH2 [357649-93-5]

Katalog-Nummer VD-OEIA-10022-10mg

Size : 10mg

Marke : VDM Biochemicals

Contact local distributor :


Telefonnummer : +1 850 650 7790

Product Specification

  • Appearance
    :

    Solid.

  • CAS Number
    :

    357649-93-5

  • Cat.number
    :

    VD-OEIA-10022

  • Formula
    :

    C14H14ClN3S

  • MW
    :

    291.8

  • Purity
    :

    >=95%

  • Solubility
    :

    DMSO

  • Storage
    :

    +2°C to +8°C. Protect from light.

  • Synonyms
    :

    HAT Inhibitor IV, Gcn5p Inhibitor, CPTH2

  • Size
    :

    10mg, 5mg

SKU: VD-OEIA-10022 Categories: Enzyme Inhibitors, Other Enzyme Inhibitors and Activators

Description

CPTH2 is a histone acetyltransferase (HAT) inhibitor modulating the Gcn5 network where HATs act as transcriptional coactivators. Histone acetylation plays an important role in regulating the chromatin structure and is tightly regulated by two classes of enzyme, histone acetyltransferases (HAT) and histone deacetylases (HDAC). Deregulated HAT and HDAC activity plays a role in the development of a range of cancers. Consequently, inhibitors of these enzymes have potential as anticancer agents.

1.Chimenti, F., et al. 2009. J. Med. Chem. 52, 530.