GLP1 (GCG) Sheep Polyclonal Antibody

Specifications

Product Data
Applications	R
Recommended Dilution	Radioimmunoassays.
Reactivities	Human
Host	Sheep
Isotype	IgG
Clonality	Polyclonal
Immunogen	Glucagon amino acids 19-29, prepared by enzymatic cleavage of Porcine glucagon, conjugated with bovine thyroglobulin carrier protein.
Specificity	This antibody is specific for the C terminal of Glucagon, a linear peptide of 29 amino acids. Its primary sequence is highly conserved among vertebrates.
Formulation	Phosphate buffered saline containing 0.09% Sodium Azide (NaN3) 1% Bovine Serum Albumin State: Purified State: Liquid purified IgG
Purification	Affinity chromatography on Protein G
Conjugation	Unconjugated
Storage	Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Gene Name	glucagon
Database Link	Entrez Gene 2641 Human UniProt ID P01275
Background	Glucagon is a hormone that is secreted by alpha cells in the pancreas. Glucagon antagonizes insulin by converting glycogen to glucose in the liver and increasing blood sugar levels. Glucagon-like peptide 1 (GLP1), Glucagon-like peptide 2 (GLP2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are in the glucagons hormone family. GLP1 is a transmitter in the central nervous system that regulates feeding and drinking behavior. GLP2 stimulates intestinal epithelial growth.
Synonyms	GCG
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein