Enoxaparin [679809-58-6]
Katalog-Nummer HY-109509-100mg
Size : 100mg
Marke : MedChemExpress
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Enoxaparin (PK 10169), a low-molecular-weight heparin (LMWH) derivative. Enoxaparin exerts anticoagulant activity through antithrombin III, an endogenous inhibitor of factor Xa and thrombin IIa. Enoxaparin protect the rat hippocampus against TBI (traumatic brain injury) via antioxidant and anti-inflammatory properties. Enoxaparin can be used for the research of deep vein thrombosis (DVT), pulmonary embolism, TBI and COVID-19.
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Enoxaparin Chemische Struktur
CAS. Nr. : 679809-58-6
This product is a controlled substance and not for sale in your territory.
Based on 1 publication(s) in Google Scholar
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| Beschreibung |
Enoxaparin (PK 10169), a low-molecular-weight heparin (LMWH) derivative. Enoxaparin exerts anticoagulant activity through antithrombin III, an endogenous inhibitor of factor Xa and thrombin IIa. Enoxaparin protect the rat hippocampus against TBI (traumatic brain injury) via antioxidant and anti-inflammatory properties. Enoxaparin can be used for the research of deep vein thrombosis (DVT), pulmonary embolism, TBI and COVID-19[1][2][3]. |
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| In Vitro |
Enoxaparin (0-70 µg/mL, 90 min) enhances AAT (alpha-1-antitrypsin) inhibition of both TMPRSS2 (Transmembrane Protease 2) activity and infection of hAEc (human airway epithelial cells) with HCoV-229E[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability Assay[1]
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| In Vivo |
Enoxaparin (1 mg/kg; SC; once every 6 h for 8 times) reduces oxidative damage, inflammation and astrocytosis following TBI (traumatic brain injury) in the rat[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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| Klinische Studie |
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| CAS. Nr. | |||||||||
| Appearance |
Solid |
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| Color |
White to off-white |
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| SMILES |
[Enoxaparin] |
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| Versand | Room temperature in continental US; may vary elsewhere. |
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| Speicherung |
4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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| Lösungsmittel & Löslichkeit |
In Vitro:
H2O : ≥ 100 mg/mL *"≥" means soluble, but saturation unknown.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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