E2F4 (Transcription Factor E2F4, E2F-4) (Biotin)

E2F4 is the most common E2F family member in a number of cell types. E2F4 deficiency has been shown to cause a decrease in the thickness of the gut epithelium, decrease in maturation of hematopoietic cell types and an increased rate of apoptosis, suggesting that E2F4 plays a role in normal maturation of several cell types. E2F4 has also been shown to be essential for the normal development of airway epithelium and early eye development. Other data has implicated E2F4 during normal heart development, specifically cardiomyocyte proliferation.

Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested.

Western Blot: 0.5ug/ml
Optimal dilutions to be determined by the researcher.

HeLa lyate cells

Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Mab

IgG1,k

LLF4-2

mouse

human

As Reported

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Purified by Protein G affinity chromatography.

Recombinant corresponding to human E2F4 fused to His-tag.

Recognizes human E2F4.

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.