DDX48 Antibody - middle region : HRP
Katalog-Nummer ARP36422_T100-HRP
Size : 100ul
Marke : Aviva Systems Biology
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Telefonnummer : +1 850 650 7790
DDX48 Antibody - middle region : HRP (ARP36422_T100-HRP)
| Datasheets/Manuals | Printable datasheet for anti-EIF4A3 (ARP36422_T100-HRP) antibody |
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| Predicted Species Reactivity | Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast, Zebrafish |
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| Product Format | Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6. |
| Clonality | Polyclonal |
| Host | Rabbit |
| Conjugation | HRP: Horseradish Peroxidase |
| Application | WB |
| Reconstitution and Storage | All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil). Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding. |
| Immunogen | The immunogen is a synthetic peptide directed towards the middle region of human DDX48 |
| Predicted Homology Based on Immunogen Sequence | Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 100% |
| Peptide Sequence | Synthetic peptide located within the following region: QCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLV |
| Concentration | 0.5 mg/ml |
| Blocking Peptide | For anti-EIF4A3 (ARP36422_T100-HRP) antibody is Catalog # AAP36422 (Previous Catalog # AAPP08478) |
| Sample Type Confirmation | EIF4A3 is supported by BioGPS gene expression data to be expressed in HepG2 |
| Reference | Lee,S., et al., (2002) Cancer Lett. 184 (2), 197-206 |
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| Gene Symbol | EIF4A3 |
| Gene Full Name | Eukaryotic translation initiation factor 4A3 |
| Alias Symbols | Fal1, RCPS, DDX48, MUK34, NUK34, NMP265, eIF4AIII, eIF4A-III, eIF-4A-III |
| NCBI Gene Id | 9775 |
| Protein Name | Eukaryotic initiation factor 4A-III |
| Description of Target | DDX48 encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a nuclear matrix protein. Its amino acid sequence is highly similar to the amino acid sequences of the translation initiation factors eIF4AI and eIF4AII, two other members of the DEAD box protein family. |
| Uniprot ID | P38919 |
| Protein Accession # | NP_055555 |
| Nucleotide Accession # | NM_014740 |
| Protein Size (# AA) | 411 |
| Molecular Weight | 45kDa |
| Protein Interactions | CDCA7L; PDCD4; HUWE1; POLDIP3; HAUS1; SUMO2; SUMO3; STAU1; UBC; LIN28B; SUMO1; WWOX; EED; RNF2; BMI1; SUZ12; ANP32A; PKM; NPLOC4; IPO11; PDLIM5; PLIN3; SRP14; RAD23B; AARS; FBXO6; SRPK2; SRPK1; UPF1; SMG1; RBM8A; ITGA4; CWC22; EEF2K; VCAM1; FN1; TRA2B; HN |
