CD44 antibody - C-terminal region

Katalog-Nummer ARP61023_P050

Size : 100ul

Marke : Aviva Systems Biology

Contact local distributor :


Telefonnummer : +1 850 650 7790

Rating:
100% of 100
Datasheets/ManualsPrintable datasheet for anti-CD44 (ARP61023_P050) antibody
Product Info
Tested Species ReactivityHuman
Predicted Species ReactivityHuman, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Product FormatLiquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
ClonalityPolyclonal
HostRabbit
ApplicationWB
Reconstitution and StorageFor short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
ImmunogenThe immunogen is a synthetic peptide directed towards the C terminal region of human CD44
PurificationAffinity Purified
Predicted Homology Based on Immunogen SequenceCow: 79%; Dog: 86%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%
Peptide SequenceSynthetic peptide located within the following region: SGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQN
Concentration0.5 mg/ml
Blocking PeptideFor anti-CD44 (ARP61023_P050) antibody is Catalog # AAP61023 (Previous Catalog # AAPP47152)
Sample Type Confirmation

CD44 is strongly supported by BioGPS gene expression data to be expressed in MD-MB231

Publications

Monika Hartmann, et al. Tumor Suppressor NF2 Blocks Cellular Migration by Inhibiting Ectodomain Cleavage of CD44. 879-90 (2015). 25652588

Description
Gene SymbolCD44
Gene Full NameCD44 molecule (Indian blood group)
Alias SymbolsIN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, HUTCH-I, ECMR-III
NCBI Gene Id960
Protein NameCD44 antigen
Description of TargetThe protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined.
Uniprot IDP16070
Protein Accession #NP_001001391
Nucleotide Accession #NM_001001391
Protein Size (# AA)361
Molecular Weight40kDa
Protein InteractionsUBC; NF2; NEDD8; BAG1; DPP8; VHL; SRC; ANK1; ATF2; FMNL1; IQGAP1; SLC3A2; STAT3; ITGB1; FLOT2; EP300; CAV1; PRKCZ; ELAVL1; ARHGEF12; ARHGEF1; PKN1; DMP1; HMMR; TIAM1; ERBB4; VAV2; GARS; TGFBR2; TGFBR1; CD4; MMP7; SRGN; SPP1; LCK; IGFBP3; CD74; FYN; FGF2;
  1. What is the species homology for "CD44 Antibody - C-terminal region (ARP61023_P050)"?

    The tested species reactivity for this item is "Human". This antibody is predicted to have homology to "Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit".

  2. How long will it take to receive "CD44 Antibody - C-terminal region (ARP61023_P050)"?

    This item is available "Domestic: within 1-2 days delivery | International: 1-2 days".

  3. What buffer format is "CD44 Antibody - C-terminal region (ARP61023_P050)" provided in?

    This item is provided in "Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.".
    Additional format options may be available. For more information please contact info@avivasysbio.com.

  4. What are other names for "CD44 Antibody - C-terminal region (ARP61023_P050)"?

    This target may also be called "IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1, CDW44, CSPG8, HCELL, HUTCH-I, ECMR-III" in publications.

  5. What is the shipping cost for "CD44 Antibody - C-terminal region (ARP61023_P050)"?

    The shipping cost for this item is within the US. Please contact us for specific shipping for international orders.

  6. What is the guarantee for "CD44 Antibody - C-terminal region (ARP61023_P050)"?

    All Aviva products have been through rigorous validations and carry 100% satisfaction guarantee.

  7. Can I get bulk pricing for "CD44 Antibody - C-terminal region (ARP61023_P050)"?

    You can get bulk pricing for this item by going here.

  8. What is the molecular weight of the protein?

    The molecular weight reported by Uniprot for this item is "40kDa".
    Please note observed molecular weights in western blot applications may differ depending on a variety of protein characteristics.

  9. What protocols are available for "CD44 Antibody - C-terminal region (ARP61023_P050)"?

    We may have detailed protocol data avaialble for this item. To learn more, please view the "Protocols & Data" tab on the product page.

  10. What are positive controls for "CD44"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  11. What are negative controls for "CD44"?

    We have listed RNA Seq and gene expression data in the "Target Info" tab. You may be able to find adequate positive controls there.

  12. What other proteins interact with "CD44"?

    This protein has been reported to interact with "Protein Interactions". Please view the "Related Categories" tab on the product page for more information.

  13. What biological processes are associated with "CD44"?

    This protein has been associated with "Biological Processes". Please view the "Related Categories" tab on the product page for more information.

  14. What cellular components are associated with "CD44"?

    This protein has been associated with "Cellular Components". Please view the "Related Categories" tab on the product page for more information.

  15. What protein functions are associated with "CD44"?

    This protein has been associated with "Protein Functions". Please view the "Related Categories" tab on the product page for more information.

Sie könnten auch an folgenden Produkten interessiert sein:



Katalog-Nummer
Beschreibung
Cond.
Preis zzgl. MwSt.
ARP60993_P050
 100ul