CD159a (CD159a, CD159a Antigen, Killer Cell Lectin like Receptor Subfamily C Member 1, KLRC1, MGC13374, MGC59791, Natural Killer Cell Lectin, NKG2, NKG2 B, NKG2-A/B-Activating NK Receptor, NKG2-A/NKG2-B Type II integral Membrane Protein, NKG2A, NKG2A, NKG2B, rNKG2A)

Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.

Suitable for use in Western Blot. Other applications not tested.

Western Blot: 1:500-1:1000
Optimal dilutions to be determined by the researcher.

May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Pab

IgG

rabbit

human

~1mg/ml

Supplied as a liquid PBS, pH 7.2, 0.05% sodium azide

Purified by immunoaffinity chromatography.

Synthetic peptide corresponding to the N-terminal of human CD159a/KLRC1

Recognizes endogenous levels of human CD159a/KLRC1

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.