CD117 Mouse Monoclonal Antibody [Clone ID: OTI2B12]
CAT#: CF808739
Carrier-free (BSA/glycerol-free) KIT mouse monoclonal antibody, clone OTI2B12 (formerly 2B12)
Formulation: Standard
Specifications
| Product Data | |
| Clone Name | OTI2B12 |
| Applications | IHC, WB |
| Recommended Dilution | WB 1:2000, IHC 1:150 |
| Reactivities | Human |
| Host | Mouse |
| Isotype | IgG2b |
| Clonality | Monoclonal |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 27-308 of human KIT(NP_000213) produced in E.coli. |
| Formulation | Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose) |
| Reconstitution Method | For reconstitution, we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process. (OriGene recommends Zeba Spin Desalting Columns, 7KMWCO from Thermo Scientific) |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 109.7 kDa |
| Gene Name | Homo sapiens KIT proto-oncogene, receptor tyrosine kinase (KIT), transcript variant 1, mRNA. |
| Database Link | |
| Background | This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Synonyms | C-Kit; CD117; PBT; SCFR |
| Reference Data | |
| Protein Families | Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Protein Kinase, Stem cell - Pluripotency, Transmembrane |
| Protein Pathways | Acute myeloid leukemia, Cytokine-cytokine receptor interaction, Endocytosis, Hematopoietic cell lineage, Melanogenesis, Pathways in cancer |
Documents
| Product Manuals |
| FAQs |
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| SDS |
Resources
| Antibody Resources |
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Other Versions
| SKU | Description | Size | |
|---|---|---|---|
| TA808739 | KIT mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) | 447,00 EUR | |
| TA808739AM | KIT mouse monoclonal antibody, clone OTI2B12 (formerly 2B12), Biotinylated | 509,00 EUR | |
| TA808739BM | KIT mouse monoclonal antibody, clone OTI2B12 (formerly 2B12), HRP conjugated | 509,00 EUR | |
| TA808739S | KIT mouse monoclonal antibody, clone OTI2B12 (formerly 2B12) | 200,00 EUR |