General Info
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-C14orf37 (700-774) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
| Gene Symbol: | ARMH4 |
| Gene ID: | 145407 |
| Uniprot ID: | ARMD4_HUMAN |
| Immunogen Region: | 700-774 |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 700-774 of human C14orf37 (NP_001001872.2). |
| Immunogen Sequence: | WMEKLKDKAGYMSGMLVPVG VGIAGALFILGALYSIKVMN RRRRNGFKRHKRKQREFNSM QDRVMLLADSSEDEF |
Description
| Tissue Specificity | Expressed in podocytes. |
| Function | May modulate immune response and may play a role in inflammation. Down-modulates STAT3 signaling throught direct interaction with IL6ST, resulting in the inhibition of phosphorylation of STAT3 at 'Tyr-705'. May negatively regulates AKT signaling by modulating the activity of mTORC2 complex through RICTOR interaction. |
| Protein Name | Armadillo-Like Helical Domain-Containing Protein 4Upstream Of Mtorc2 Protein |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Armadillo-Like Helical Domain-Containing Protein 4 antibodyAnti-Upstream Of Mtorc2 Protein antibodyAnti-ARMH4 antibodyAnti-C14orf37 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance