General Info
Host: | Goat |
Applications: | Pep-ELISA/WB |
Reactivity: | Human |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Goat polyclonal antibody anti-BPI (Internal) is suitable for use in ELISA and Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Concentration: | 0.5 mg/mL |
Dilution Range: | WB-0.3-1µg/mlELISA-antibody detection limit dilution 1:128000. |
Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Information
Gene Symbol: | BPI |
Gene ID: | 671 |
Uniprot ID: | BPI_HUMAN |
Immunogen Region: | Internal |
Accession Number: | NP_001716.2 |
Immunogen Sequence: | KIPDYSDSFKIKH |
Description
Function | The cytotoxic action of BPI is limited to many species of Gram-negative bacteria.this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa. |
Protein Name | Bactericidal Permeability-Increasing ProteinBpiCap 57 |
Database Links | Reactome: R-HSA-166016Reactome: R-HSA-6798695Reactome: R-HSA-6803157 |
Cellular Localisation | SecretedCytoplasmic Granule MembraneMembrane-Associated In Polymorphonuclear Leukocytes (Pmn) Granules |
Alternative Antibody Names | Anti-Bactericidal Permeability-Increasing Protein antibodyAnti-Bpi antibodyAnti-Cap 57 antibodyAnti-BPI antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance