AMPK alpha-1/2 (Thr183/Thr172) Antibody, PE Conjugated
Katalog-Nummer bs-4002R-PE
Size : 100ul
AMPK alpha-1/2 (Thr183/Thr172) Antibody, PE Conjugated
Applications
Reactivity
Predicted Reactivity
Overview | |
Catalog # | bs-4002R-PE |
Product Name | AMPK alpha-1/2 (Thr183/Thr172) Antibody, PE Conjugated |
Applications | WB, FCM |
Reactivity | Human, Mouse, Rat, Pig, Sheep |
Predicted Reactivity | Dog, Cow, Horse, Chicken |
Specifications | |
Conjugation | PE |
Host | Rabbit |
Source | KLH conjugated synthetic phosphopeptide derived from mouse AMPK alpha 2 around the phosphorylation site of Thr172 |
Modification Site | Thr172/Thr183 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Gene ID | 5562 |
Subcellular location | Cytoplasm, Nucleus |
Synonyms | PRKAA1phospho T172; AMPK alpha 1 + AMPK alpha 2 phospho T183/T172; 5 AMP activated protein kinase alpha 1catalytic subunit; 5 AMP activated protein kinase catalytic alpha 1 chain; 5' AMP activated protein kinase catalytic subunit alpha 1; AAPK1; acetyl CoA carboxylase kinase; AI194361; AI450832; AL024255; AMP -activate kinase alpha 1 subunit; AMP-activated protein kinase, catalytic, alpha -1; AMPK 1; AMPK alpha 1 chain; AMPK; AMPK1; AMPKa1; AMPKalpha1; C130083N04Rik; cb116; EC 2.7.11.1; HMG CoA reductase kinase;hormone sensitive lipase kinase; im:7154392; kinase AMPK alpha1; MGC33776; MGC57364; PRKAA 1; PRKAA1; Protein kinase AMP activated alpha 1 catalytic subunit; SNF1-like protein AMPK; wu:fa94C10. |
Background | The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]. |
Application Dilution | |
WB | 1:300-5000 |
FCM | 1:20-100 |