Ampicillin (sodium) [69-52-3]
Katalog-Nummer HY-B0522A-5g
Size : 5g
Marke : MedChemExpress
Ampicillin sodium (D-(-)-α-Aminobenzylpenicillin sodium salt) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.
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Ampicillin sodium Chemische Struktur
CAS. Nr. : 69-52-3
This product is a controlled substance and not for sale in your territory.
Based on 33 publication(s) in Google Scholar
Other Forms of Ampicillin sodium:
- Ampicillin In-stock
- Ampicillin trihydrate In-stock
Beschreibung |
Ampicillin sodium (D-(-)-α-Aminobenzylpenicillin sodium salt) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria[1]. |
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IC50 & Target |
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In Vitro |
Ampicillin inhibits the growth of E. coli of swine origin in a dose-dependent manner. The effective inhibitory concentration of Ampicillin was 2.5 uG/mL[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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In Vivo |
Ampicillin is very effective in alleviating the symptoms of hemorrhagic enteritis in a 11-week old pig[1]. Ampicillin produces maximum concentrations in bile twice as high as in serum. The peak concentration of ampicillin after an oral dose is as twice as high in portal blood as in peripheral blood[2]. Ampicillin provides neuroprotection against ischemia-reperfusion brain injury. Ampicillin reduces the activities of MMPs and increases the expression level of GLT-1. Pretreatment with ampicillin significantly reduces medial hippocampal cell death following global forebrain ischemia[3]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
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Klinische Studie |
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Molekulargewicht |
371.38 |
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Formel |
C16H18N3NaO4S |
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CAS. Nr. |
69-52-3 |
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Appearance |
Solid |
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Color |
White to off-white |
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SMILES |
O=C([C@@H]1N(C2=O)[C@]([C@@H]2NC([C@@H](C3=CC=CC=C3)N)=O)(22)SC1(C)C)O[Na] |
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Versand | Room temperature in continental US; may vary elsewhere. |
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Speicherung |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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Lösungsmittel & Löslichkeit |
In Vitro:
H2O : ≥ 200 mg/mL (538.53 mM) DMSO : 200 mg/mL (538.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO) *"≥" means soluble, but saturation unknown. Preparing
Stock Solutions
View the Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles. * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol) Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2 In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
For the following dissolution methods, please prepare the working solution directly.
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
Dosage mg/kgAnimal weight Dosing volume Number of animals Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration:
mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
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Reinheit & Dokumentation |
Purity: ≥98.0% |
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Verweise |
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Complete Stock Solution Preparation Table
*
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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H2O / DMSO | 1 mM | 2.6927 mL | 13.4633 mL | 26.9266 mL | 67.3165 mL |
5 mM | 0.5385 mL | 2.6927 mL | 5.3853 mL | 13.4633 mL | |
10 mM | 0.2693 mL | 1.3463 mL | 2.6927 mL | 6.7316 mL | |
15 mM | 0.1795 mL | 0.8976 mL | 1.7951 mL | 4.4878 mL | |
20 mM | 0.1346 mL | 0.6732 mL | 1.3463 mL | 3.3658 mL | |
25 mM | 0.1077 mL | 0.5385 mL | 1.0771 mL | 2.6927 mL | |
30 mM | 0.0898 mL | 0.4488 mL | 0.8976 mL | 2.2439 mL | |
40 mM | 0.0673 mL | 0.3366 mL | 0.6732 mL | 1.6829 mL | |
50 mM | 0.0539 mL | 0.2693 mL | 0.5385 mL | 1.3463 mL | |
60 mM | 0.0449 mL | 0.2244 mL | 0.4488 mL | 1.1219 mL | |
80 mM | 0.0337 mL | 0.1683 mL | 0.3366 mL | 0.8415 mL | |
100 mM | 0.0269 mL | 0.1346 mL | 0.2693 mL | 0.6732 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.