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> AEBSF hydrochloride [30827-99-7]

AEBSF hydrochloride [30827-99-7]

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Katalog-Nummer HY-12821-100mg

Size : 100mg

Marke : MedChemExpress

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AEBSF hydrochloride is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.

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AEBSF hydrochloride Chemische Struktur

AEBSF hydrochloride Chemische Struktur

CAS. Nr. : 30827-99-7

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AEBSF hydrochloride Related Antibodies

WB
Cell Viability Assay
    Western blotting analysis of the expression level of pATF6, CHOP, Cleaved Caspase12 and Bax in shRNA-Cs1429 and shRNA-Cs1429+AEBSF cells.
    The proliferation capacity of shRNA-Cs1429 transfected cells, by treatment with AEBSF (200 μmol/l), is the highest among all the groups.

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    AEBSF hydrochloride is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.

    In Vitro

    AEBSF inhibits the constitutive production of Aβ by directly inhibiting β-secretase in five different human cell lines, both neural and nonneural.
    AEBSF, as a serine protease inhibitor, inhibits the lysis of leukemic cells by human macrophages without inhibiting macrophage secretion of TNF-α and IL-1β.
    AEBSF also disturbs the growth of blastocysts on endometrial cells and inhibit the adhesion of HeLa cells on HUVECs by altering the protein secretion pattern.

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.

    AEBSF hydrochloride Related Antibodies

      Help & FAQs
      • Do most proteins show cross-species activity?

        Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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