ACADVL, also known as VLCAD, LCACD or ACAD6, is an inner mitochondrial membrane protein that belongs to the family of acyl-CoA dehydrogenases. This protein is involved in lipid metabolism and has catalytic activity toward esters of long chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA, and functions in the first step of the fatty acid beta-oxidation pathway. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Recombinant human ACADVL protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Synonyms
ACAD6, LCACD, VLCAD, Very long-chain specific acyl-CoA dehydrogenase, mitochondrial
Liquid, in 20 mM Tris-HCl (pH 8.0) containing 10% Glycerol
Concentration
1 mg/ml (determined by Bradford assay)
Purity
> 90 % by SDS-PAGE
Storage
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
References
Smelt AH., et al. (1998) Ann Neurol. 43(4):540-4. Souri M., et al. (1996) Am J Hum Genet. 58(1):97-106.
Supplier
ARP
View product citations for antibody 01-1752-VL on CiteAb
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